Michael G. Bartlett, Ph.D.
Associate Professor









EDUCATION

1990 - B.S. Chemistry
North Carolina State University, Raleigh, North Carolina

1994 - Ph.D. Analytical Chemistry
Georgia Institute of Technology, Atlanta, Georgia

1995 - Postdoctoral Research Fellow, Medicinal Chemistry
University of Utah, Salt Lake City, Utah

EMPLOYMENT HISTORY

1995-2001    Assistant Professor
                    Department of Pharmaceutical and Biomedical Sciences
                    University of Georgia
                    Athens, GA 30602-2352

1997-2001    Adjunct Assistant Professor
                    Department of Pathology and Laboratory Medicine
                    Emory University School of Medicine
                    Atlanta, GA 30322

1998-2001    Assistant Professor
                    Interdisciplinary Toxicology Program
                    University of Georgia
                    Athens, GA 30602

2001-present Associate Professor
                    Department of Pharmaceutical and Biomedical Sciences
                    University of Georgia
                    Athens, GA 30602-2352

2001-present Associate Professor
                    Interdisciplinary Toxicology Program
                    University of Georgia
                    Athens, GA 30602

PROFESSIONAL HONORS AND AWARDS

2003 Chemist of the Year for Service, Northeast Georgia Chapter of the American Chemical Society

2002 Named College of Pharmacy Teacher of the Year

2001 Named Phi Delta Chi, College of Pharmacy Teacher of the Year

2000 American Association of Colleges of Pharmacy New Investigator Award

2000 Named Phi Delta Chi, College of Pharmacy Teacher of the Year

1999 American Society for Mass Spectrometry Young Investigator Award

1994 Outstanding Dissertation Award, Georgia Institute of Technology

1994 Hermann Flashka Award for Outstanding Graduate Research, Georgia Institute of Technology, School of Chemistry and Biochemistry

1990 Award from International Society for the Study of Xenobiotics for Significant Contribution to the
Field of Xenobiotics

PUBLICATIONS

R.B. van Breemen, M.G. Bartlett, Y. Tsou, C. Culver, H. Swaisgood and S.E. Unger
“Degradation of Peptide Drugs by Immobilized Digestive Proteases.”
Drug Metabolism and Disposition, 19(3), 683-689 (1991).

M.G. Bartlett and K.L. Busch
“Transmission Characteristics of a Radio-Frequency Quadrupole for MS/MS.”
Analytical Instrumentation, 21(3&4), 123-140 (1993).

M.G. Bartlett and K.L. Busch
“Liquid Secondary Ion Mass Spectra of 2-Iminothiolane  Derivatives.”
Biological Mass Spectrometry, 23, 353-356 (1994).

K.R. Mohan, M.G. Bartlett, K.L. Busch, A.E. Schoen and N. Gore
“Calibration Point for  Electron Ionization MS/MS Spectra Measured with Multiquadrupole Mass Spectrometers.”
Journal of the American Society for Mass Spectrometry, 5, 576-582 (1994).

M.G. Bartlett and K.L. Busch
“Product Ion Nodes in MS/MS.”
Instrumentation Science and Technology, 22(4), 301-312 (1994).

M.G. Bartlett, S.A. Burns, D.A. Bruce and K.L. Busch
“Alumatrane Revisited: Distribution of Oligomeric Ions in Electron Ionization, Chemical Ionization, and Liquid Secondary Ion Mass Spectra.”
Journal of Mass Spectrometry, 30, 741-746 (1995).

M.G. Bartlett, K.L. Busch, C.A. Wells and K.L. Schey
“Use of 2-Hydroxy-1-naphthoic Acid as a Matrix for Matrix-Assisted Laser Desorption Ionization Mass Spectrometry of Low Molecular Weight Porphyrins and Peptides.”
Journal of Mass Spectrometry, 31, 275-279 (1996).

M.G. Bartlett, J.A. McCloskey, S. Manalili and R.E. Griffey
“The Role of Charge in the Collision-Induced Dissociation of Oligonucleotides.”
Journal of Mass Spectrometry, 31, 1277-1283 (1996).

M.G. Bartlett, G.M. Haas, D.A. Bruce, S.M. Thomas, J.A. Bertrand, M.G. White and K.L. Busch
“Characterization of Supported and Unsupported Transition Metal Complexes by Mass Spectrometry.”
Analytica Chimica Acta, 346(2), 223-236 (1997).

P.P. Wang, L.B. Martin and M.G. Bartlett
“Electrospray Collision-Induced Dissociation  Mass Spectra of Positively-Charged Oligonucleotides.”
Rapid Communications in Mass  Spectrometry, 11, 846-856 (1997).

R.J. Geiger, K.L. Busch and M.G. Bartlett
“Cluster/Adduct Ions in Liquid Secondary Ion  Mass Spectrometry Mass Spectra of Metal Acetylacetonates are Formed Exclusively in Beam-Induced Reactions”
European Mass Spectrometry, 3(3), 248-250 (1997).

D.L. Tumbula, Q. Teng, M.G. Bartlett and W.B. Whitman
“Ribose Biosynthesis and Evidence for an Alternative First Step in the Common Aromatic Amino Acid Pathway in Methanococcus Maripaludis.”
Journal of Bacteriology, 179(19), 6010-6013 (1997).

L.P. Kotra, P.P. Wang, M.G. Bartlett, K. Shanmuganathan, Z. Xu, S. Cavalcanti, M.G.  Newton and C.K. Chu
“4-Azido-2-pyrimidone Nucleosides and Related Chemistry.”
Journal of  Organic Chemistry, 62, 7267-7271 (1997).

M.G. Bartlett, D.A. Bruce and K.L. Busch
“Ions Formed by Reaction between Solvent and Sample in the Liquid Secondary Ion Mass Spectra of Some Metal Acetylacetonates.”
Applied Spectroscopy, 51, 1757-1760 (1997).

K.L. Busch and M.G. Bartlett
“Bioanalysis Applications, Electrospray Ionization, and  MALDI Take Center Stage at the 45th Annual ASMS Conference.”
Spectroscopy, 12(10), 112- 113 (1997).

K. Srinivasan and M.G. Bartlett
“Capillary Electrophoresis Stereoselective Determination of  R(+) and S(-) Pentobarbital from Serum Using Hydroxypropyl-gamma-cyclodextrin, Solid Phase Extraction and UV Detection.”
Journal of Chromatography B: Biomedical Applications, 703,  289-294 (1997).

K. Srinivasan and M.G. Bartlett
“Rapid and Simultaneous Capillary Electrophoresis Determination of (R)- and (S)-Secobarbital from Serum and Prediction of Hydroxypropyl- gamma-Cyclodextrin-Secobarbital Stereoselective Interaction Using Molecular Mechanics Simulation.”
Journal of Chromatographic Science, 36, 85-90 (1998).

M.C. Melnyk, R.E. Carlson, K.L. Busch, K.L. Schey and M.G. Bartlett
“Probing the  Energetics of Charge-Remote Fragmentation Mechanisms in Carbocyanine Dyes Using  Collision- and Surface-Induced Dissociation Mass Spectrometry.”
Journal of Mass Spectrometry, 33, 75-84 (1998).

H. Zhang, P.P. Wang, M.G. Bartlett and J.T. Stewart
“HPLC Determination of  Cisatracurium Besylate and Propofol Mixtures with LC-MS Identification of Degradation  Products.”
Journal of Pharmaceutical and Biomedical Analysis, 16, 1241-1249 (1998).

T.G. Venkateshwaran, J.T. Stewart, R.T. Bishop, J.A. deHaseth and M.G. Bartlett
“Solution Conformation of Model Peptides With the Use of Particle Beam LC/FT-IR Spectrometry and Electrospray Mass Spectrometry.”
Journal of Pharmaceutical and Biomedical Analysis, 17, 57-67 (1998).

P.P. Wang, H. Zhang, J.T. Stewart and M.G. Bartlett
“Simultaneous Detection of Cisatracurium, its Degradation Products and Propofol Using Positive Ion Detection Followed by Negative Ion Detection in a Single LC/MS Run.”
Journal of Pharmaceutical and Biomedical Analysis, 17, 547-553 (1998).

J.C. Spell, K. Srinivasan, J.T. Stewart and M.G. Bartlett
“Supercritical Fluid Extraction and Negative Ion Electrospray LC/MS/MS Analysis of Phenobarbital, Butalbital, Pentobarbital and Thiopental from Human Serum.”
Rapid Communications in Mass Spectrometry, 12, 890-894 (1998).

M.C. Melnyk, K.L. Schey, M.G. Bartlett and K.L. Busch
“Charge-Remote Fragmentation in Dialkylaminostyryl Dyes.”
Journal of Mass Spectrometry, 33, 850-857 (1998).

P.P. Wang and M.G. Bartlett
“The Collision-Induced Dissociation Mass Spectra of Cocaine, its Metabolites and Pyrolysis Products.”
Journal of Mass Spectrometry, 33, 961-967 (1998).

M.G. Bartlett, J.C. Spell, P.S. Mathis, M.F.A. Elghany, B.E. Elzeany, M.A. Elkawy and J.T. Stewart
“Determination of Degradation Products From the Calcium-Channel Blocker Isradipine.”
Journal of Pharmaceutical and Biomedical Analysis, 18, 335-345 (1998).

P.P. Wang and M.G. Bartlett
“Identification and Quantitation of Cocaine N-Oxide: A Thermally Labile Metabolite of Cocaine.”
Journal of Analytical Toxicology, 23:(1), 62-66 (1999).

H.G. Cutler, S.J. Cutler, S.A. Ross, K. El Sayed, F.M. Dugan, M.G. Bartlett, A.A. Hill, R.A. Hill and S.R. Parker
"Koninginin G, A New Metabolite from Trichoderma aureoviride.”
Journal of Natural Products, 62:(1), 137-139 (1999).

R.J. Geiger, M.C. Melnyk, K.L. Busch and M.G. Bartlett
“Modifications to an Analytical Mass Spectrometer for the Soft-Landing Experiment.”
International Journal of Mass Spectrometry, 182/183, 415-422 (1999).

P.P. Wang, L.P. Kotra, C.K. Chu and M.G. Bartlett
“Structural Characterization of 4-Azido-2-Pyrimidinone Nucleoside Analogs Using Mass Spectrometry.”
Journal of Mass Spectrometry, 34, 724-732 (1999).

T.G. Venkateshwaran, J.T. Stewart, J.A. deHaseth and M.G. Bartlett
“Solution  Conformation of Model Polypeptides With the Use of Particle Beam LC/FT-IR Spectrometry  and Electrospray Mass Spectrometry.”
Journal of Pharmaceutical and Biomedical  Analysis, 19, 709-723 (1999).

K.S. Kraft, P.C. Ruenitz and M.G. Bartlett
"Carboxylic Acid Analogues of Tamoxifen: (Z)-2-[p-(1,2-Diphenyl-1-betenyl)phenoxy]-N,N-dimethylethylamine. Estrogen Receptor Affinity and Estrogen Antagonist Effects in MCF-7 Cells.”
Journal of Medicinal Chemistry, 42, 3126-3133 (1999).

Y. Xia, P.P. Wang, M.G. Bartlett, H.M. Solomon and K.L. Busch
“An LC-MS-MS Method for the Comprehensive Analysis of Cocaine and Cocaine Metabolites in Meconium.”
Analytical Chemistry, 72, 764-771 (2000).

K. Vishwanathan, M.G. Bartlett and J.T. Stewart
“Determination of Antimigraine Compounds Rizatriptan, Zolmitriptan, Naratriptan and Sumatriptan in Human Serum by Liquid Chromatography Electrospray Tandem Mass Spectrometry.”
Rapid Communications in Mass Spectrometry, 14, 168-172 (2000).

K. Srinivasan, P.P. Wang, A.T. Eley, C.A. White and M.G. Bartlett
“Liquid Chromatography-Tandem Mass Spectrometry Analysis of Cocaine and its Metabolites From Blood, Amniotic Fluid, Placental and Fetal Tissue: Study of the Metabolism and Distribution of Cocaine in the Pregnant Rats.”
Journal of Chromatography B: Biomedical Applications, 745, 287-303 (2000).

K. Srinivasan and M.G. Bartlett
“Comparison of Cyclodextrin-Barbiturate Noncovalent Complexes Using Electrospray Ionization Mass Spectrometry and Capillary Electrophoresis.”
Rapid Communications in Mass Spectrometry, 14, 624-632 (2000).

K. Srinivasan and M.G. Bartlett
“Capillary Electrophoresis Determination of Butalbital From Serum Using Solid Phase Extraction and Ultraviolet Detection.”
Journal of Liquid Chromatography and Related Technologies, 23, 2361-2371 (2000).

K. Vishwanathan, R.L. Tackett, J.T. Stewart and M.G. Bartlett
“Determination of Dimethylarginine and L-Arginine in Human Plasma by Liquid Chromatography Tandem Mass Spectrometry.”
Journal of Chromatography B: Biomedical Applications, 748, 157-166 (2000).

X. Xu, M.G. Bartlett and J.T. Stewart
“Determination of Ondansetron and its Hydroxy Metabolites in Human Serum Using Solid Phase Extraction and Positive Ion Electrospray LC/MS/MS.”
Journal of Mass Spectrometry, 35, 1329-1334 (2000).

T.N. Clark, C.A. White C.K. Chu and M.G. Bartlett
“Determination of 3’-Azido-2’,3’ Dideoxyuridine (AZDU) in Maternal Plasma, Amniotic Fluid, Fetal and Placental Tissues by High Performance Liquid Chromatography.”
Journal of Chromatography B: Biomedical Applications, 755, 165-172 (2001).

K. Vishwanathan, M.G. Bartlett and J.T. Stewart
“Determination of Gatifloxacin in Human Plasma by Liquid Chromatography Electrospray Tandem Mass Spectrometry.”
Rapid Communications in Mass Spectrometry, 15, 915-919 (2001).

X. Xu, M.G. Bartlett and J.T. Stewart
“Determination of Degradation Products from Sumatriptan Succinate Using LC-MS and LC-MS-MS.”
Journal of Pharmaceutical and Biomedical Analysis, 26, 367-377 (2001).

M.G. Bartlett and K.A. Morrow
“Method for Assessing Course Knowledge in a Large Classroom Environment: An Improved Version of the Minute Paper.”
American Journal of Pharmaceutical Education, 65, 264-267 (2001).

D.C. Delinsky, K. Srinivasan, H.M. Solomon and M.G. Bartlett
“Simultaneous Capillary Electrophoresis Determination of Barbiturates From Meconium.”
Journal of Liquid Chromatography and Related Technologies, 25(1), 113-123 (2002).

S.D. Brown, C.A. White, C.K. Chu and M.G. Bartlett
“Determination of Acyclovir in Maternal Plasma, Amniotic Fluid, Fetal and Placental Tissue by High Performance Liquid Chromatography.”
Journal of Chromatography B: Biomedical Applications, 772(2), 327-334 (2002).

B. Fan, M.G. Bartlett and J.T. Stewart
“Determination of Lamivudine / Stavudine / Efavirenz in Human Serum Using Liquid Chromatography Electrospray Tandem Mass Spectrometry.”
Biomedical Chromatography, 16, 383-389 (2002).

Y. Al-nouti and M.G. Bartlett
“Comparison of Local Anesthetic – Cyclodextrin Non-Covalent Complexes Using Capillary Electrophoresis and Electrospray Ionization Mass Spectrometry.”
Journal of the American Society for Mass Spectrometry, 13, 928-935 (2002).

S.D. Brown, C.A. White and M.G. Bartlett
“Hydrophobic Interaction Liquid Chromatography Electrospray Mass Spectrometry Determination of Acyclovir in Pregnant Rat Plasma and Tissues.”
Rapid Communications in Mass Spectrometry, 16, 1871-1876 (2002).

K. Vishwanathan, M.G. Bartlett and J.T. Stewart
“Determination of Moxifloxacin in Human Plasma by Liquid Chromatography Electrospray Tandem Mass Spectrometry.”
Journal of Pharmaceutical and Biomedical Analysis, 30, 961-968 (2002).

S.D. Brown, C.A. White and M.G. Bartlett
“High Performance Liquid Chromatographic Determination of Acyclovir and Zidovudine in Maternal Plasma, Amniotic Fluid, Fetal and Placental Tissues Using Ultraviolet Detection.”
Journal of Liquid Chromatography and Related Technologies, 25, 2857-2871 (2002).

S.D. Brown, S. Muralidhara, J.V. Bruckner and M.G. Bartlett
“Trace Level Determination of Trichloroethylene from Liver, Lung and Kidney Tissues by Gas Chromatography / Mass Spectrometry.”
Journal of Chromatography B: Biomedical Applications, 783, 319-325 (2003).

S.D. Brown, M.G. Bartlett and C.A. White
“Comparative Pharmacokinetics of Intravenous Acyclovir and Acyclovir / Zidovudine Therapies in the Pregnant Rat."
Antimicrobial Agents and Chemotherapy, 47, 991-996 (2003).

S.D. Brown, A.M. Dixon, J.V. Bruckner and M.G. Bartlett
“A Validated GC-MS Assay for the Quantitation of Trichloroethylene (TCE) from Drinking Water.”
International Journal of Environmental Analytical Chemistry, 83, 427-432 (2003).

M.G. Bartlett
“Biochemistry of Water Soluble Vitamins: A Lecture for First Year Pharmacy Students.”
American Journal of Pharmaceutical Education, In Press

D.C. Delinsky, E.J. Abu-Raddad and M.G. Bartlett
“Chiral Capillary Electrophoresis Determination of 2’,3’-Dideoxy-5-Fluoro-3’-Thiacytidine in Rat Plasma.”
Journal of Liquid Chromatography and Related Technologies, In Press

Y. Al-nouti and M.G. Bartlett
“Simultaneous Quantitation of Zidovudine and Zidovudine Monophosphate from Plasma, Amniotic Fluid and Tissues by Micellar Capillary Electrophoresis.”
Biomedical Chromatography, In Press

Y. Ding, C.A. White, S. Muralidhara, J.V. Bruckner and M.G. Bartlett
“Determination of Deltamethrin and its Metabolite 3-Phenoxybenzoic Acid in Male Rat Plasma by High-Performance Liquid Chromatography.”
Journal of Chromatography B, In Press

T.N. Clark, M.G. Bartlett, C.K. Chu and C.A. White,
“Placental Transport of Zidovudine (AZT) and Azidouridine (AZDU) in the Pregnant Rat.”
Biopharmaceutics and Drug Disposition, Submitted

Y. Alnouti, C.A. White, and M.G. Bartlett
“Determination of Lamivudine in Plasma, Amniotic Fluid, and Tissues from the Pregnant Rat by High Performance Liquid Chromatography.”
Journal of Chromatography B, Submitted

D.C. Delinsky, K.T. Hill, C.A. White and M.G. Bartlett
“Quantitation of the Large Polypeptide Glucagon by Protein Precipitation and LC-MS.”
Journal of Mass Spectrometry, Submitted

Y. Ding, C.A. White, and M.G. Bartlett
“Determination of 2’,3’-dideoxycytidine in maternal plasma, amniotic fluid, placental and fetal tissues by high-performance liquid chromatography.”
Journal of Chromatography B, Submitted

D.C. Delinsky, K.T. Hill, C.A. White and M.G. Bartlett
“Quantitation of the Polypeptide Galanin by Protein Precipitation and External Calibration LC-MS.”
Journal of Chromatography B, Submitted

D.C. Delinsky, K.T. Hill, C.A. White and M.G. Bartlett
“Quantitation of the Polypeptide Motilin by Protein Precipitation and LC-MS.”
Rapid Communications in Mass Spectrometry, Submitted

T.N. Clark, C.A. White and M.G. Bartlett
“Determination of Abacavir in Maternal Plasma, Amniotic Fluid, Fetal and Placental Tissues by a Polarity Switching LC/MS/MS Method.”
Rapid Communications in Mass Spectrometry, Submitted

T.N. Clark, C.A. White and M.G. Bartlett
“Determination of Didanosine in Maternal Plasma, Amniotic Fluid, Fetal and Placental Tissues by LC/MS/MS.”
Journal of Mass Spectrometry, Submitted